On this page
Herbal and dietary supplement-associated liver injury is uncommon relative to how many people take supplements, and it accounts for a growing share of drug-induced liver injury cases.
What the surveillance shows
Registries tracking drug-induced liver injury have reported an increasing proportion of cases attributed to herbal and dietary supplements over recent decades. Some cases are severe, and supplement-associated cases have appeared among causes of acute liver failure requiring transplantation. The absolute numbers remain small relative to total supplement use, but the pattern is well enough documented to take seriously.
Which categories
Bodybuilding products, particularly those containing anabolic steroids whether declared or not, are heavily represented. Weight-loss products, sometimes containing undeclared pharmaceutical adulterants. Green tea extract at high concentration has a documented signal and has prompted regulatory advisories in some jurisdictions. Kava has been restricted in several countries over hepatotoxicity. Case reports exist for a range of botanicals including ashwagandha, turmeric preparations and others.
Cognizil: six named ingredients, no caffeine, 60-day money-back guarantee.
See Cognizil PricingWarning signs and what to do
Yellowing of the skin or eyes, dark urine, pale stools, persistent right upper abdominal pain, unusual fatigue, nausea and loss of appetite. Any of these while taking a supplement warrants stopping it and seeking medical attention promptly. Keep the product and its batch number, because identifying the cause matters both for you and for surveillance. Report the event to your national adverse event system - in the US, the FDA's MedWatch programme.
Key takeaways
- Supplements account for a growing share of drug-induced liver injury cases
- Bodybuilding and weight-loss products are heavily represented in registries
- Green tea extract and kava have documented hepatotoxicity signals
- Jaundice, dark urine and right upper abdominal pain warrant stopping and seeking care
Cognizil in context
Nothing on this page is a claim about Cognizil specifically. Cognizil is a dietary supplement providing nutrient support for memory, focus and mental clarity; it is not a treatment for any condition and should not be used as one. For an honest read on whether it is worth the money, our value for money review states both sides. Current Cognizil sale pricing is on the official order page.
Cognizil™ — Official Site Pricing
Liquid advanced memory support with Ginkgo Biloba, Bacopa Monnieri, St. John’s Wort, N-Acetyl L-Carnitine, Huperzine-A and Phosphatidylserine. Stimulant-free, taken once daily by dropper.
Check Cognizil AvailabilityFrom $49 per bottle on the 6-bottle tier · free US shipping on 6 bottles · 60-day money-back guaranteeInteraction notice: contains St. John’s Wort. If you take any prescription medicine, including hormonal contraception, check the interaction list and speak to a pharmacist first.